As a leader in Blow-Fill-Seal technology for over thirty years, NovaCina offers unit dose and multidose formats with unrivaled, high-speed manufacturing. We offer a wide variety of dosage forms and a broad range of expertise and differentiated solutions. With 120M+ unit capacity and expertise at every stage of the drug development life cycle from early-stage drug development to full-scale manufacturing, distribution, tech-transfer, stability studies, and life cycle management, we have the capabilities to support you in delivering your product to market ahead of schedule.
Blow-fill-seal is an advanced aseptic processing and packaging technology. It is a completely automated and enclosed formulation and filling system that manufactures, fills, and seals ampoules in a single process, significantly reducing the risk of contamination compared relative to traditional vial and bottle filling operations. NovaCina’s blow-fill-seal technology offers a variety of volumes and presentations enabling our clients to bring innovative delivery systems to market.
Capabilities: NovaCina offers products aseptically filled and terminally sterilized in low-density polyethylene plastic ampoules.
- Ampoule fill volumes range from 1mL to 30mL
- Wide range of batch sizes from 105L to 25,000L
- 120M+ unit capacity
- Wide range of head-molds available:
- Luer connection – direct fit with syringe (1mL – 10mL)
- Non-Luer connection – draw with needle (5mL – 20mL)
- Inhalation connection – 1mL – 2.5mL
- Irrigation connection – 30 mL
- Flow wrapping capability
Blow-Fill-Seal capabilities are delivered using:
- Highly automated Rommelag advanced aseptic processing technology
- Automated inspection technology
- Integrated robotics for downstream handling and packaging
- 7x Rommelag Blow-Fill-Seal machines
- 24x7 operating capacity
NovaCina specializes in the production of sterile single dose plastic presentations which offers many benefits relative to multi-dose and glass presentations including:
- Tamper-proof and counterfeit-resistant presentations ensures precise dosing and dosage compliance in all settings, reducing medical and legal risks for patients, providers, and payors
- Shatter resistant presentations with no sharp edges reduces the risk of injury to patients and facility personnel
- Preservative free formulation options
- Freezable containers
